Abstract
Background This study evaluates the impact of gender in dialysis-dependent patients undergoing
cardiac surgery.
Methods We retrospectively identified 204 dialysis-dependent patients (68.6% male, aged 66.6 ± 9.9
years) with end-stage renal disease undergoing cardiac surgery and compared them to
a propensity-score-pair-matched control collective.
Results A 30-day mortality was 13.2% (14/106) for coronary artery bypass grafting (CABG),
19.3% (6/31) for aortic valve replacement (AVR), and 23.8% (16/67) for combined procedures.
Postoperative chest tube output was significantly higher in men (1,007 ± 946 mL) versus
women (687 ± 598 mL, p = 0.014). Compared with a propensity-score-pair-matched control collective of 204
patients, we identified significant differences in terms of 30-day mortality: overall
mortality revealed 17.6 versus 4.6% (p = 0.0001), 13.2 versus 3.4% (p = 0.014) for CABG, 19.3 versus 0% (p = 0.051) for AVR, and 23.8 versus 9.1% (p = 0.02) for combined procedures.
Conclusion Multivariate analysis identified preoperative myocardial infarction, prolonged extracorporeal
circulation time, operation time, and surgical reexploration as independent predictors
of 30-day mortality. There was a higher occurrence of bleeding complications in men
that remained significant even after correction for body surface area.
Keywords
cardiac - kidney (includes related subject matter) - coronary artery bypass grafting
(CABG) surgery - heart valve stenosis
